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DETAILS
FUNCTION
Application
COA| Items | Specification | Result | Method |
|---|---|---|---|
| Content | S-Adenosyl-L-methionine Disulfate Tosylate 95.0%~103.0%(On dried basis) | 100% | HPLC || USP |
| Content | 1. S, S-Isomer NLT 75.0% | 81.5% | HPLC || USP |
| 2. SAM-e ION 49.5%~54.7% | 52.2% | HPLC || USP | |
| 3. P-Toluenesulfonic Acid 21.0%~24.0% | 22.6% | HPLC || USP | |
| 4. Sulfate (SO4 ) 23.5%~26.5% | 25.2% | HPLC || USP | |
| Related substances | 1. S-ADENOSYL-L-HOMOCYSTEINE NMT 1.0% | 0.05% | HPLC || USP |
| 2. ADENINE NMT 1.0% | 0.25% | HPLC || USP | |
| 3. METHYLTHIOADENOSINE NMT 1.0% | 0.18% | HPLC || USP | |
| 4. ADENOSINE NMT 1.0% | 0.02% | HPLC || USP | |
| 5. TOTAL IMPURITIES NMT 3.5% | 0.89% | HPLC || USP | |
| Identification | 1. The retention time of the major peak corresponds to the reference sample | Conform | HPLC || USP |
| 2. Infrared absorption spectrum complies to the Reference Spectrum | Conform | Mid-Infrared spectroscopy || USP |
| Solubility | Free solubility in water | Conform | Organoleptic |
|---|---|---|---|
| Particle Size | NLT 95% Through 60 mesh | 100% | Analytical sieving || USP |
| Water Content(K.F) | NMT 3.0% | 1.3% | USP |
| Sulphated Ash | NMT 0.5% | 0.1% | USP |
| pH(5% Aqueous Solution) | 1.0~2.0 | 1.2 | USP |
| Heavy Metals(as Pb) | NMT 10ppm | <10ppm | USP Method II |
|---|---|---|---|
| Arsenic (As) | NMT 2ppm | <2ppm | ICP-MS || USP |
| Lead (Pb) | NMT 3ppm | <3ppm | ICP-MS || USP |
| Cadmium (Cd) | NMT 1ppm | <1ppm | ICP-MS || USP |
| Mercury (Hg) | NMT 0.1ppm | <0.1ppm | ICP-MS || USP |
| Total Plate Count | NMT 10,000cfu/g | <10cfu/g | USP |
|---|---|---|---|
| Total Yeast & Mold | NMT 1,000cfu/g | <10cfu/g | USP |
| E. Coli | Not Detected in(g) 10 | Not Detected | USP |
| Salmonella | Not Detected in(g) 25 | Not Detected | USP |
| Staphylococcus | Not Detected in(g) 10 | Not Detected | USP |
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