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Hydrochloride Berberine HCl Granular Powder
  • Hydrochloride Berberine HCl Granular Powder

Hydrochloride Berberine HCl Granular Powder

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halal
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kosher
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SKU:
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Unit:
kg
Product Name:
Hydrochloride Berberine HCl Granular (Berberine Granules)
Latin Name:
Phellodendron amurense Rupr. or Berberis aristata
Specification:
97.0% / 98.0% Berberine HCl (HPLC / Titration)
Appearance:
Bright Yellow Granular Powder
Certificate:
USDA Organic, EU Organic, ISO9001, HACCP, KOSHER, HALAL
Shelf Life:
24 Months when properly stored
Storage:
Store in a cool, dry, and clean place. Keep away from strong light, intense heat, and ambient moisture
Package:
Packed in 25kg paperboard drums with two food-grade plastic inner bags sealed tightly to prevent moisture absorption.

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What is Hydrochloride Berberine HCl Granular?

HBerberine HCl Granular is a clinically validated metabolic and glycemic-control ingredient extracted from premium Phellodendron amurense and Berberis aristata. Standardized with ≥97%–98% high-purity berberine hydrochloride, it delivers stable and efficient nutritional efficacy for metabolic regulation. Optimized for industrial application, this granular formula features superior density, excellent flowability and dust-free performance, effectively solving the static and dust problems of traditional fine powder. It serves as an ideal active material for capsule filling, tablet pressing and high-end cardio-metabolic health supplements.

Master AMPK Activation & Glycemic Optimization

Acts as one of the most potent natural activators of Adenosine Monophosphate-Activated Protein Kinase (AMPK), often celebrated as the body's metabolic master switch. Clinical data repeatedly confirms its unique capability to drastically improve peripheral insulin sensitivity, stimulate glucose uptake in skeletal muscle tissues, and safely stabilize postprandial blood sugar parameters.

Targeted De Novo Lipogenesis & Fat Blockade

Downregulates key adipogenic transcription factors and selectively blocks the differentiation of preadipocytes into mature fat cells. By regulating lipid metabolism pathways, it reduces circulating triglycerides, lowers low-density lipoprotein (LDL) scores, and actively targets stubborn visceral fat accumulation.

Intensive Gut Microbiome & Endotoxin Regulation

Exerts powerful broad-spectrum antimicrobial actions within the lower intestinal tract, selectively inhibiting opportunistic pathogens while preserving beneficial commensal bacteria. This localized flora modulation decreases circulating lipopolysaccharides (LPS) and strengthens the intestinal mucosal barrier, addressing systemic low-grade inflammation from the inside out..

Cardiovascular Endothelial & Nitric Oxide Support

Promotes endothelial nitric oxide synthase (eNOS) activity, inducing smooth muscle relaxation in vascular pathways. This targeted cardiovascular protection preserves arterial elasticity, safely assists healthy blood pressure parameters, and mitigates long-term chronic metabolic vascular aging.

Heavy-Duty Cardio-Metabolic Tablets & Capsules

The premier choice for manufacturing high-premium blood sugar support tablets, insulin sensitivity complexes, and general metabolic wellness capsules. Our standardized granulate format ensures maximum commercial synergy alongside Chromium Picolinate, Alpha-Lipoic Acid, or Cinnamon Extract.

Biohacking Carb-Control & Non-Stimulant Weight Management Capsules

An exceptional active inclusion for next-generation "anti-aging sugar blockers," ketogenic carb-interceptors, and wellness-focused weight-loss lines. Because its botanical bioactives safely optimize glucose disposal channels without triggering the unwanted heart palpitations, neurological jitters, or subsequent sleep disruptions linked to standard caffeine stimulants, it empowers premium health-hacking brands to successfully target corporate executives, low-carb dieters, and healthy-aging demographics.

High-Efficiency Industrial Manufacturing Optimization

Specially engineered for supplement contract manufacturers (CMOs/CDMOs) handling high-speed automated encapsulation and tableting lines. Its dense granular geometry completely eliminates hopper bridging, guarantees precise weight uniformity per dose, and mitigates industrial dusting cross-contamination risks, drastically slashing machinery maintenance downtime and cleaning labor costs.

Gastrointestinal Detoxification & Herbal GI Cleanses

Ideally suited for engineering short-term intensive herbal GI detox regimens, anti-candida capsules, and deep systemic internal purification complexes aimed at optimizing long-term digestive and metabolic integrity.

COA
Items Specification Result Method
Content Berberine HCl ≥97.0% 97.1% HPLC || USP
Identification Correspond to standard Conform TLC || USP

PHYSICAL CHARACTERISTICS

PHYSICAL CHARACTERISTICS
Odor&Taste Characteristic Conform Organoleptic
Particle Size NLT 95% Through 80 mesh 98% Analytical sieving || USP
Loss on Drying NMT 12.00% 10.9% USP
Total Ash NMT 0.2% 0.1% USP
Bulk Density NLT 20g/100ml 24g/100ml USP Method I
Tapped Density NLT 40g/100ml 41g/100ml USP Method I

CHEMICAL CHARACTERISTICS

CHEMICAL CHARACTERISTICS
Residual Solvent NMT 5000ppm Conform GC || USP
Pesticide Residue Meet the requirements Conform GC || USP
Heavy Metals(as Pb) NMT 10ppm <10ppm USP Method II
Arsenic (As) NMT 2ppm 0.07ppm ICP-MS || USP
Lead (Pb) NMT 2ppm 0.10ppm ICP-MS || USP
Cadmium (Cd) NMT 1ppm 0.05ppm ICP-MS || USP
Mercury (Hg) NMT 1ppm <0.01ppm ICP-MS || USP

MICROBIOLOGICAL CHARACTERISTICS

MICROBIOLOGICAL CHARACTERISTICS
Total Plate Count NMT 10,000cfu/g 100cfu/g USP
Total Yeast & Mold NMT 1,000cfu/g 20cfu/g USP
Coliforms NMT 10MPN/g <10MPN/g USP
E. Coli Not Detected in(g) 10 Not Detected USP
Salmonella Not Detected in(g) 25 Not Detected USP
Staphylococcus Not Detected in(g) 10 Not Detected USP