Milk Thistle Extract Powder
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What is Milk Thistle Extract?
Targeted Hepatoprotection & Detoxification
Silymarin acts as a powerful cell-membrane stabilizer, preventing toxins from binding to liver cell receptors while stimulating protein synthesis to accelerate hepatic tissue regeneration. Clinical research confirms its capability to reduce elevated liver enzymes caused by alcohol, fatty liver, or environmental pollutant burdens..
Advanced Antioxidant & Glutathione Boost
It significantly enhances the body's endogenous defense mechanisms by boosting levels of glutathione and superoxide dismutase (SOD) within the liver. This synergistic antioxidant cascade effectively scavenges lipid peroxides, shielding vital organs from long-term oxidative stress.
Inflammatory Response Modulation
Helps inhibit the NF-kB signaling pathway, reducing the production of pro-inflammatory cytokines and preventing chronic fibrotic tissue accumulation. This renders it highly effective in therapeutic formulations designed to mitigate chronic inflammatory stress in hepatic and digestive tissues.
Metabolic & Cardiovascular Support
Assists in optimizing cholesterol synthesis in the liver, contributing to a healthier lipid profile and balanced blood glucose levels. Its broad metabolic benefits help brand owners position it in multifunctional formulas targeting metabolic syndrome and overall metabolic longevity.
Dietary Supplements & Nutraceuticals
Perfectly suited for hard capsules, tablets, and softgels aimed at liver detox, anti-fatigue, and alcohol metabolism support. It offers proven formulation synergy when blended with Artichoke extract, Dandelion root, or Schisandra extract for high-end wellness markets.
Functional Foods & Hangover Cures
Our specialized water-soluble Silymarin grade is highly stable and ideal for innovative hangover-relief shots, ready-to-drink (RTD) wellness beverages, and effervescent tablets. It allows food scientists to tap directly into the surging global demand for natural, fast-acting sober-up and liver-defense consumer goods.
Cosmetics & Anti-Aging Care
Increasingly incorporated into clean-beauty skincare ranges to protect the dermal layer against UV-induced oxidative damage and environmental pollutants. Its unique soothing and metabolic properties help calm inflammatory skin conditions while enhancing topical skin barrier resilience.
| Items | Specification | Result | Method |
| Silymarin (UV) | NLT 80.0% | 84.75% | UV || USP |
| Silymarin (HPLC) | NLT 45.0% | 47.33% | HPLC || USP |
| Sum of Silybin & Isosilybin (HPLC) | NLT 30.0% | 33.1% | HPLC || USP |
| Sum of Silybin A + Silybin B | 40~65% | 57.95% | HPLC || USP |
| Sum of Isosilybin A + Isosilybin B | 10~20% | 11.99% | HPLC || USP |
| Sum of Silycristin + Silydianin | 20~45% | 30.06% | HPLC || USP |
| Identification | A. TLC Test: Correspond to standard | Conform | TLC || USP |
| B. HPLC Identification Test: Correspond to standard | Conform | HPLC || USP | |
| PHYSICAL CHARACTERISTICS | |||
| Appearance | Yellow to light brown powder | Light brown Powder | Organoleptic |
| Particle Size | NLT 95% Through 80 mesh | 96% | Analytical sieving || USP |
| Loss on Drying | NMT 5.00% | 1.42% | USP |
| Sulphated Ash | NMT 0.50% | 0.28% | USP |
| Bulk Density | Between 0.30~0.60g/100ml | 0.462g/ml | USP Method I |
| Tapped Density | Between 0.50~0.90g/100ml | 0.866g/ml | USP Method I |
CHEMICAL CHARACTERISTICS
| Residual Solvent (Acetone) | NMT 5,000ppm | 3357.7ppm | GC || USP |
| Arsenic (As) | NMT 2ppm | <1ppm | ICP-MS || USP |
| Lead (Pb) | NMT 2ppm | <1ppm | ICP-MS || USP |
| Cadmium (Cd) | NMT 1ppm | <1ppm | ICP-MS || USP |
| Mercury (Hg) | NMT 1ppm | <0.1ppm | ICP-MS || USP |
MICROBIOLOGICAL CHARACTERISTICS
| Total Plate Count | NMT 10,000cfu/g | <1,000cfu/g | USP |
| Total Yeast & Mold | NMT 1,000cfu/g | <100cfu/g | USP |
| Coliforms | NMT 10MPN/g | <10MPN/g | USP |
| E. Coli | Not Detected in(g) 10 | Not Detected | USP |
| Salmonella | Not Detected in(g) 25 | Not Detected | USP |
| Staphylococcus | Not Detected in(g) 10 | Not Detected | USP |