Name: Milk Thistle Extract, Silymarin Powder, Silybum marianum Extract, Milk Thistle Extract Manufacturer, Water Soluble Silymarin, Liver Protection Ingredients, JHD Nutrasource
Availability: InStock

DETAILS
FUNCTION
Application
COA

DETAILS

What is Milk Thistle Extract?

Milk Thistle Extract Powder, derived from the premium seeds of Silybum marianum, is a cornerstone botanical ingredient manufactured by JHD Nutrasource. Utilizing advanced, eco-friendly solvent extraction and crystallization processing, our extract is highly standardized to contain exceptional levels of Silymarin, the primary active complex renowned for its therapeutic properties.

FUNCTION

Targeted Hepatoprotection & Detoxification

Silymarin acts as a powerful cell-membrane stabilizer, preventing toxins from binding to liver cell receptors while stimulating protein synthesis to accelerate hepatic tissue regeneration. Clinical research confirms its capability to reduce elevated liver enzymes caused by alcohol, fatty liver, or environmental pollutant burdens..

Advanced Antioxidant & Glutathione Boost

It significantly enhances the body's endogenous defense mechanisms by boosting levels of glutathione and superoxide dismutase (SOD) within the liver. This synergistic antioxidant cascade effectively scavenges lipid peroxides, shielding vital organs from long-term oxidative stress.

Inflammatory Response Modulation

Helps inhibit the NF-kB signaling pathway, reducing the production of pro-inflammatory cytokines and preventing chronic fibrotic tissue accumulation. This renders it highly effective in therapeutic formulations designed to mitigate chronic inflammatory stress in hepatic and digestive tissues.

Metabolic & Cardiovascular Support

Assists in optimizing cholesterol synthesis in the liver, contributing to a healthier lipid profile and balanced blood glucose levels. Its broad metabolic benefits help brand owners position it in multifunctional formulas targeting metabolic syndrome and overall metabolic longevity.

Application

Dietary Supplements & Nutraceuticals

Perfectly suited for hard capsules, tablets, and softgels aimed at liver detox, anti-fatigue, and alcohol metabolism support. It offers proven formulation synergy when blended with Artichoke extract, Dandelion root, or Schisandra extract for high-end wellness markets.

Functional Foods & Hangover Cures

Our specialized water-soluble Silymarin grade is highly stable and ideal for innovative hangover-relief shots, ready-to-drink (RTD) wellness beverages, and effervescent tablets. It allows food scientists to tap directly into the surging global demand for natural, fast-acting sober-up and liver-defense consumer goods.

Cosmetics & Anti-Aging Care

Increasingly incorporated into clean-beauty skincare ranges to protect the dermal layer against UV-induced oxidative damage and environmental pollutants. Its unique soothing and metabolic properties help calm inflammatory skin conditions while enhancing topical skin barrier resilience.

COA

Items	Specification	Result	Method
Silymarin (UV)	NLT 80.0%	84.75%	UV \|\| USP
Silymarin (HPLC)	NLT 45.0%	47.33%	HPLC \|\| USP
Sum of Silybin & Isosilybin (HPLC)	NLT 30.0%	33.1%	HPLC \|\| USP
Sum of Silybin A + Silybin B	40~65%	57.95%	HPLC \|\| USP
Sum of Isosilybin A + Isosilybin B	10~20%	11.99%	HPLC \|\| USP
Sum of Silycristin + Silydianin	20~45%	30.06%	HPLC \|\| USP
Identification	A. TLC Test: Correspond to standard	Conform	TLC \|\| USP
	B. HPLC Identification Test: Correspond to standard	Conform	HPLC \|\| USP
PHYSICAL CHARACTERISTICS
Appearance	Yellow to light brown powder	Light brown Powder	Organoleptic
Particle Size	NLT 95% Through 80 mesh	96%	Analytical sieving \|\| USP
Loss on Drying	NMT 5.00%	1.42%	USP
Sulphated Ash	NMT 0.50%	0.28%	USP
Bulk Density	Between 0.30~0.60g/100ml	0.462g/ml	USP Method I
Tapped Density	Between 0.50~0.90g/100ml	0.866g/ml	USP Method I

CHEMICAL CHARACTERISTICS

Residual Solvent (Acetone)	NMT 5,000ppm	3357.7ppm	GC \|\| USP
Arsenic (As)	NMT 2ppm	＜1ppm	ICP-MS \|\| USP
Lead (Pb)	NMT 2ppm	＜1ppm	ICP-MS \|\| USP
Cadmium (Cd)	NMT 1ppm	＜1ppm	ICP-MS \|\| USP
Mercury (Hg)	NMT 1ppm	＜0.1ppm	ICP-MS \|\| USP

MICROBIOLOGICAL CHARACTERISTICS

Total Plate Count	NMT 10,000cfu/g	＜1,000cfu/g	USP
Total Yeast & Mold	NMT 1,000cfu/g	＜100cfu/g	USP
Coliforms	NMT 10MPN/g	＜10MPN/g	USP
E. Coli	Not Detected in(g) 10	Not Detected	USP
Salmonella	Not Detected in(g) 25	Not Detected	USP
Staphylococcus	Not Detected in(g) 10	Not Detected	USP